Translational research in neurology and neuroscience 2011: movement disorders.

P77: NADPH Oxidase Type 4 Inhibits Immune Cell Trafficking into The Central Nervous System During Neuroinflammation

Transendothelial trafficking of immune cells into the central nervous system (CNS) and disruption of the blood brain barrier (BBB) are pathophysiological hallmarks of neuroinflammatory disorders like multiple sclerosis (MS). Accumulating evidence suggest that oxidative stress plays a major role in the pathogenesis of MS, whereas a specific influence of oxidative stress on BBB dysfunction in MS ...

The World of Neurology Comes Together at the AAN Annual Meeting

T he 2014 Annual Meeting of the American Academy of Neurology (AAN) attracted more than 13,000 neurology professionals to Philadelphia, a city rich in its own neurology-related history. More than 2,500 presentations of cutting-edge research were available to attendees from across the world. The number of non-U.S. attendees was nearly 4,000. Science and continuing medical education are the main ...

Primary Sensorimotor Cortex Drives the Common Cortical Network for Gamma Synchronization in Voluntary Hand Movements

1 Department of Neurology, Semmelweis University, Budapest, Hungary, 2 Section of Movement Disorders and Neurostimulation, Biomedical Statistics and Multimodal Signal Processing Unit, Department of Neurology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany, 3 Department of Neurology, Christian-Albrechts-Univers...

Wittgenstein, medicine and neuropsychiatry.

A historical review is presented of the link between Ludwig Wittgenstein, considered the most important philosopher of the 20th century, and medicine, particularly neurology and psychiatry. Wittgenstein worked as a porter at Guy's Hospital in London, and then as a technician at the Royal Victoria Infirmary in Newcastle. He wrote about his important insights into language, and neuroscience. It h...

Psychogenic movement disorders: a crisis for neurology.